Reliable change indices for the Italian version of the Montreal Cognitive Assessment (MoCA) in non-demented Parkinson’s disease patients

期刊论文
出版模式：

开放获取
发表日期：

2024年11月4日

查看全文

Edoardo Nicolò Aiello,
Federica Solca,
Silvia Torre,
Beatrice Curti,
Giulia De Luca,
Ruggero Bonetti,
Francesco Scheveger,
Eleonora Colombo,
Alessio Maranzano,
Marco Olivero,
Claudia Morelli,
Alberto Doretti,
Luca Maderna,
Federico Verde,
Roberta Ferrucci,
Sergio Barbieri,
Fabiana Ruggiero,
Denise Mellace,
Angelica Marfoli,
Angelica De Sandi,
Alberto Priori,
Gabriella Pravettoni,
Vincenzo Silani,
Nicola Ticozzi,
Andrea Ciammola,
Barbara Poletti

摘要

Background

. The present study aimed at deriving regression-based reliable change indices (RCIs) for the Montreal Cognitive Assessment (MoCA) in an Italian cohort of non-demented Parkinson’s disease (PD) patients.

Methods

N = 33 consecutive, non-demented PD patients were followed-up at a 5-to-8-month interval (M = 6.6; SD = 0.6) with the MoCA. Practice effects and test-retest reliability were assessed via dependent-sample t-tests and intra-class correlation (ICC) coefficients, respectively. RCIs were derived separately for raw and demographically adjusted MoCA scores according to a standardized regression-based approach by accounting for both baseline confounders (i.e., demographics, disease duration and Unified Parkinson’s Disease Rating Scale scores) and retest interval.

Results

No practice effects were found (t(32) = 0.29; p = .778), with acceptable test-retest reliability being detected (ICC = 0.67). MoCA scores at T0 proved to be the only significant predictor of T1 MoCA performances within both the model addressing raw scores and that addressing adjusted scores (ps < 0.001).

Conclusions

The present study provides Italian practitioners and researchers with regression-based RCIs for the MoCA in non-demented PD patients, which can be reliably adopted for retest interval ≥ 5 and ≤ 8 months without encountering any practice effect.