Cushing’s syndrome developing myasthenia gravis with takotsubo cardiomyopathy after adrenalectomy: a case report

期刊论文
出版模式：

开放获取
发表日期：

2024年9月20日

查看全文

Ken Yamamoto,
Takeshi Kuroda,
Satomi Kubota,
Kaoru Matsuoka,
Shota Kosuge,
Yutaro Momma,
Ayako Miki,
Hidetomo Murakami

摘要

Background

Several cases of autoimmune disease onset after treatment for Cushing’s syndrome have been reported.

Case presentation

Herein, we report a case of myasthenia gravis crisis in a 51-year-old woman 2 months after adrenalectomy for adrenal Cushing’s syndrome accompanied by takotsubo cardiomyopathy. The resolution of excessive endogenous cortisol after adrenalectomy may have triggered the onset of previously latent myasthenia gravis.

Conclusions

Observing the similarities in symptoms between myasthenia gravis and adrenal crisis, which can sometimes be challenging to differentiate, is essential. Moreover, the presence of takotsubo cardiomyopathy as a non-motor manifestation of myasthenic crisis must be noted.