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Background <p>The weekend effect refers to the observation that patients admitted to the hospital on the weekend experience poorer clinical outcomes than patients admitted during the workweek. This effect has not been previously studied among patients hospitalised for chronic kidney disease (CKD) in Poland. This study aimed to evaluate the association between weekend admission and in-hospital mortality among patients hospitalised for CKD in Poland.</p> Methods <p>This was a retrospective study of nationwide administrative hospital discharge records of adult patients admitted with a primary diagnosis of CKD between January 1, 2017, and December 31, 2021, in Poland. The association between weekend admission and in-hospital mortality and the effect modification by admission mode were evaluated using multivariable logistic regression. Sensitivity analyses using alternative weekend definitions were conducted to test the robustness of the findings.</p> Results <p>In total, 184 299 hospitalisations were analysed, of which 24 945 (13.5%) occurred on the weekend. Overall, weekend admission was found to be associated with higher adjusted odds of in-hospital mortality compared with weekday admission (aOR:1.501[1.419–1.587]; <i>p</i> &lt; 0.001). This association differed by admission mode (p for interaction = 0.003), with higher adjusted odds of in-hospital mortality among emergency admissions (aOR:1.541[1.454–1.633]; <i>p</i> &lt; 0.001), and no statistically significant association among scheduled admissions. The results of sensitivity analyses were largely consistent with the primary results.</p> Conclusions <p>A significant association between weekend admission and increased odds of in-hospital mortality among patients hospitalised for CKD in Poland was observed. This association was statistically significant among emergency admissions but not scheduled admissions. These findings highlight the need to evaluate weekend hospital care pathways and further investigate the pre-hospital and in-hospital factors that may contribute to the observed disparities in outcomes in this patient population.</p>

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Impact of weekend admission on in-hospital mortality in chronic kidney disease: a nationwide analysis of 184 299 hospitalisations in Poland (2017–2021)

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  • 发表日期：

    2026年3月7日

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  • Agnieszka Mazurek,
  • Mateusz Jankowski,
  • Justyna Grudziąż-Sękowska

摘要

Background

The weekend effect refers to the observation that patients admitted to the hospital on the weekend experience poorer clinical outcomes than patients admitted during the workweek. This effect has not been previously studied among patients hospitalised for chronic kidney disease (CKD) in Poland. This study aimed to evaluate the association between weekend admission and in-hospital mortality among patients hospitalised for CKD in Poland.

Methods

This was a retrospective study of nationwide administrative hospital discharge records of adult patients admitted with a primary diagnosis of CKD between January 1, 2017, and December 31, 2021, in Poland. The association between weekend admission and in-hospital mortality and the effect modification by admission mode were evaluated using multivariable logistic regression. Sensitivity analyses using alternative weekend definitions were conducted to test the robustness of the findings.

Results

In total, 184 299 hospitalisations were analysed, of which 24 945 (13.5%) occurred on the weekend. Overall, weekend admission was found to be associated with higher adjusted odds of in-hospital mortality compared with weekday admission (aOR:1.501[1.419–1.587]; p < 0.001). This association differed by admission mode (p for interaction = 0.003), with higher adjusted odds of in-hospital mortality among emergency admissions (aOR:1.541[1.454–1.633]; p < 0.001), and no statistically significant association among scheduled admissions. The results of sensitivity analyses were largely consistent with the primary results.

Conclusions

A significant association between weekend admission and increased odds of in-hospital mortality among patients hospitalised for CKD in Poland was observed. This association was statistically significant among emergency admissions but not scheduled admissions. These findings highlight the need to evaluate weekend hospital care pathways and further investigate the pre-hospital and in-hospital factors that may contribute to the observed disparities in outcomes in this patient population.