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Purpose <p>To explore the feasibility of using low-dose computed tomography (CT) guidance in the process of radiofrequency ablation (RFA) for the treatment of liver tumours.</p> Methods <p>In this study, 150 patients requiring CT-guided RFA for liver tumours were divided into conventional-dose (250&#xa0;mA, <i>n</i> = 75) and low-dose (50&#xa0;mA, <i>n</i> = 75) groups based on the guided CT dose. Image quality and radiation dose were compared between the two groups.</p> Result <p>The CT images of both groups met the requirements for RFA treatment, and the treatment was successfully completed. The radiation dose parameters in the conventional-dose group were a volume CT dose index of 19.14 ± 7.16 mGy, a dose-length product of 4,987.19 ± 1,679.80 mGy·cm and an effective dose (ED) of 74.81 ± 28.20 mSv. The ED in the low-dose group was 74.8% lower than that in the conventional-dose group (<i>p</i> &lt; 0.05). The CT images of both groups met the requirements for RFA treatment, with the low-dose group exhibiting lower image quality but clear visualisation of the radiofrequency electrode needle in the liver tumours. At the 1–3-month follow-up, the complete ablation rates were comparable between the low-dose (78.86%) and conventional-dose (79.12%) groups (<i>p</i> &gt; 0.05), demonstrating short-term technical success.</p> Conclusion <p>Low-dose CT protocols for guiding RFA may reduce the radiation dose without compromising oncologic outcomes. However, these findings should be interpreted in the context of the short-term (1–3 months) follow-up period, which assessed immediate ablation success but not long-term recurrence rates.</p> Clinical trial number <p>Not applicable.</p>

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Evaluating the feasibility and radiation dose reduction of low-dose computed tomography in radiofrequency ablation for liver tumours

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月16日

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  • Ling-Ling Gao,
  • Zhan-Hui Liu,
  • Guan-Wei Nie,
  • De-Yuan Zhao,
  • Li-Dong Zheng,
  • Jun-Lu Zhao

摘要

Purpose

To explore the feasibility of using low-dose computed tomography (CT) guidance in the process of radiofrequency ablation (RFA) for the treatment of liver tumours.

Methods

In this study, 150 patients requiring CT-guided RFA for liver tumours were divided into conventional-dose (250 mA, n = 75) and low-dose (50 mA, n = 75) groups based on the guided CT dose. Image quality and radiation dose were compared between the two groups.

Result

The CT images of both groups met the requirements for RFA treatment, and the treatment was successfully completed. The radiation dose parameters in the conventional-dose group were a volume CT dose index of 19.14 ± 7.16 mGy, a dose-length product of 4,987.19 ± 1,679.80 mGy·cm and an effective dose (ED) of 74.81 ± 28.20 mSv. The ED in the low-dose group was 74.8% lower than that in the conventional-dose group (p < 0.05). The CT images of both groups met the requirements for RFA treatment, with the low-dose group exhibiting lower image quality but clear visualisation of the radiofrequency electrode needle in the liver tumours. At the 1–3-month follow-up, the complete ablation rates were comparable between the low-dose (78.86%) and conventional-dose (79.12%) groups (p > 0.05), demonstrating short-term technical success.

Conclusion

Low-dose CT protocols for guiding RFA may reduce the radiation dose without compromising oncologic outcomes. However, these findings should be interpreted in the context of the short-term (1–3 months) follow-up period, which assessed immediate ablation success but not long-term recurrence rates.

Clinical trial number

Not applicable.