Bacterial culture and antibiotic resistance pattern in chronic rhinosinusitis among patients who underwent sinus surgery
摘要
Chronic rhinosinusitis (CRS) is a common inflammatory condition affecting a large portion of the population worldwide. Bacterial infections are one of the causes of recurrence and treatment resistance in CRS. Our goal is to describe antimicrobial resistance patterns in patients with CRS who underwent functional endoscopic sinus surgery (FESS).
MethodsA retrospective chart review was conducted at King Abdulaziz University Hospital, which included 444 patients who underwent 444 FESS procedures between January 2014 and December 2018.
ResultsA total of 98% of the patients underwent primary FESS. Of the 803 cultured samples, 611 (76%) yielded bacterial growth. The most frequently isolated organisms were Staphylococcus aureus (32%), Klebsiella pneumoniae (10.6%), and Pseudomonas aeruginosa (9.7%). Gram-positive organisms were most susceptible to vancomycin and ofloxacin.
ConclusionA wide range of microorganisms were obtained from patients with CRS. The antibiotic resistance of microorganisms in CRS is an important issue because many of the pathogens are noted to be resistant to commonly used antibiotics.
Clinical trailNot applicable.