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Background <p>Hantavirus infection frequently results in hemorrhagic fever with renal syndrome, which may be fatal in certain instances. invasive pulmonary aspergillosis is a rare concurrent symptom that requires considerable attention from clinicians.</p> Case presentation <p>This report describes a case of a male patient, age 55, who had periorbital pain, fever, and oliguria but no risk indicators for invasive pulmonary aspergillosis. He was admitted to the intensive care unit due to respiratory failure, oliguria, and shock. The diagnosis of hemorrhagic fever with renal syndrome complicated by invasive pulmonary aspergillosis was confirmed by bronchoscopy and chest CT. After 45 days in the hospital, the patient recovered completely after receiving 27 days of treatment in the intensive care unit.</p> Conclusions <p>Hemorrhagic fever with renal syndrome(HFRS) complicated by invasive pulmonary aspergillosis is infrequently observed in clinical practice. Consequently, in patients with HFRS exhibiting pulmonary injury, the prompt identification of interstitial pneumonia is essential.</p>

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Rare concurrent invasive pulmonary aspergillosis in a critically Ill patient with hemorrhagic fever with renal syndrome: a case report

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  • 发表日期：

    2026年4月1日

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  • Weiwei Yan,
  • Alin Sun,
  • Liming Wang,
  • Jihong Zhang,
  • Peng Chen

摘要

Background

Hantavirus infection frequently results in hemorrhagic fever with renal syndrome, which may be fatal in certain instances. invasive pulmonary aspergillosis is a rare concurrent symptom that requires considerable attention from clinicians.

Case presentation

This report describes a case of a male patient, age 55, who had periorbital pain, fever, and oliguria but no risk indicators for invasive pulmonary aspergillosis. He was admitted to the intensive care unit due to respiratory failure, oliguria, and shock. The diagnosis of hemorrhagic fever with renal syndrome complicated by invasive pulmonary aspergillosis was confirmed by bronchoscopy and chest CT. After 45 days in the hospital, the patient recovered completely after receiving 27 days of treatment in the intensive care unit.

Conclusions

Hemorrhagic fever with renal syndrome(HFRS) complicated by invasive pulmonary aspergillosis is infrequently observed in clinical practice. Consequently, in patients with HFRS exhibiting pulmonary injury, the prompt identification of interstitial pneumonia is essential.