Scholarlink

Background <p>Human papillomavirus (HPV) infection represents a major public health concern in both women and men, contributing to a substantial anogenital and oropharyngeal disease burden. Nevertheless, comprehensive data on the genotype-specific epidemiology of HPV in the male population in Wuhan, China, are lacking. This study was conducted to address this gap.</p> Methods <p>We conducted a retrospective cross-sectional study of 2,999 male subjects undergoing HPV testing at Renmin Hospital of Wuhan University (January 2017 to July 2025) to analyze the prevalence and genotypic distribution of HPV.</p> Results <p>Among 2,999 males, overall HPV prevalence was 38.6%, predominantly low-risk single-type infections. The top five genotypes were HPV6, HPV11, HPV16, HPV52, and HPV59. Although 20–39 year-olds comprised the largest proportion of cases, peak prevalence occurred in youth (≤ 20y) and elderly (≥ 60y) groups (<i>P</i> &lt; 0.001 for age difference). HPV6 was the most common genotype in every age stratum.</p> Conclusion <p>In this group of males in Wuhan, HPV infection prevalence was relatively high and dominated by low-risk, single-type infections. Adolescents (≤ 20 years) and older men (≥ 60 years) are at highest risk. These findings support enhanced HPV education targeting youth and the elderly and broader promotion of HPV vaccination among males.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Human papillomavirus prevalence and genotypic characteristics among men in Wuhan, China: a cross-sectional study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月11日

查看全文
  • Zhiming Li,
  • Ruoxi Wu,
  • Zhiqiang Li,
  • Hong Fan,
  • Liqin Xiang,
  • Lingjun Zhao,
  • Ruyue Guo,
  • Saisai Xu,
  • Kailang Wu,
  • Chengliang Zhu

摘要

Background

Human papillomavirus (HPV) infection represents a major public health concern in both women and men, contributing to a substantial anogenital and oropharyngeal disease burden. Nevertheless, comprehensive data on the genotype-specific epidemiology of HPV in the male population in Wuhan, China, are lacking. This study was conducted to address this gap.

Methods

We conducted a retrospective cross-sectional study of 2,999 male subjects undergoing HPV testing at Renmin Hospital of Wuhan University (January 2017 to July 2025) to analyze the prevalence and genotypic distribution of HPV.

Results

Among 2,999 males, overall HPV prevalence was 38.6%, predominantly low-risk single-type infections. The top five genotypes were HPV6, HPV11, HPV16, HPV52, and HPV59. Although 20–39 year-olds comprised the largest proportion of cases, peak prevalence occurred in youth (≤ 20y) and elderly (≥ 60y) groups (P < 0.001 for age difference). HPV6 was the most common genotype in every age stratum.

Conclusion

In this group of males in Wuhan, HPV infection prevalence was relatively high and dominated by low-risk, single-type infections. Adolescents (≤ 20 years) and older men (≥ 60 years) are at highest risk. These findings support enhanced HPV education targeting youth and the elderly and broader promotion of HPV vaccination among males.