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<p>Anthrax is a zoonotic disease caused by Bacillus anthracis, typically transmitted to humans through direct or indirect contact with infected or deceased animals and their contaminated products. Brucellosis, another zoonosis, is most commonly acquired through contact with animals or their products, but is often misdiagnosed or overlooked due to its nonspecific clinical manifestations. Although each infection is relatively well documented, human coinfection with anthrax and brucellosis has not previously been reported. Here, we describe the first such case: an elderly farmer from rural northern China who was diagnosed with cutaneous anthrax concurrent with brucellosis. The case highlights that dual zoonotic infections can occur even in non-endemic areas and underscores the importance of screening brucellosis in febrile patients with a history of livestock exposure.</p>

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First documented case of cutaneous anthrax and brucellosis coinfection in a human in rural northern China: a case report

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年12月5日

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  • Yunzheng An,
  • Jiangyu Liu,
  • Xuedan Liu,
  • Fei Di,
  • Yuan Gao,
  • Lianchun Liang,
  • Feng Zhao,
  • Jianru Jia,
  • Zhenhuan Cao

摘要

Anthrax is a zoonotic disease caused by Bacillus anthracis, typically transmitted to humans through direct or indirect contact with infected or deceased animals and their contaminated products. Brucellosis, another zoonosis, is most commonly acquired through contact with animals or their products, but is often misdiagnosed or overlooked due to its nonspecific clinical manifestations. Although each infection is relatively well documented, human coinfection with anthrax and brucellosis has not previously been reported. Here, we describe the first such case: an elderly farmer from rural northern China who was diagnosed with cutaneous anthrax concurrent with brucellosis. The case highlights that dual zoonotic infections can occur even in non-endemic areas and underscores the importance of screening brucellosis in febrile patients with a history of livestock exposure.