Scholarlink

Background <p>Drug-resistant pulmonary tuberculosis (DR-TB) remains a critical public health challenge, particularly affecting vulnerable populations such as the elderly, who exhibit higher morbidity and mortality rates. This study aims to elucidate the chest CT characteristics of DR-TB in elderly patients to improve diagnostic accuracy and guide individualized treatment strategies.</p> Methods <p>A retrospective analysis of 183 confirmed DR-TB cases (Huai’an Infectious Disease Hospital, June 2013-June 2023) compared chest CT findings (lesion distribution, extent, and morphology) between elderly patients (≥ 60&#xa0;years) and non-elderly patients (14–59&#xa0;years).</p> Results <p>Key findings reveal that elderly patients demonstrate a higher frequency of extensive lung involvement, with 76% exhibiting lesions in all lung lobes compared to 40.74% in the non-elderly group (<i>P</i> &lt; 0.001). Additionally, the elderly group displayed significantly more pathological features, such as segmental and lobar shadows (61.33% vs. 45.37%, <i>P</i> = 0.033) and lung destruction (22.67% vs. 11.11%, <i>P</i> = 0.035).</p> Conclusion <p>The identification of risk factors on chest CT, including the presence of pulmonary and bronchial lesions, highlights the necessity for tailored screening and management strategies for elderly DR-TB patients.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Chest CT findings in drug-resistant pulmonary tuberculosis: a comparative analysis of elderly and non-elderly patients

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月17日

查看全文
  • Guijuan Zhu,
  • Weiguang Feng,
  • Fang Li,
  • Xin Zhang

摘要

Background

Drug-resistant pulmonary tuberculosis (DR-TB) remains a critical public health challenge, particularly affecting vulnerable populations such as the elderly, who exhibit higher morbidity and mortality rates. This study aims to elucidate the chest CT characteristics of DR-TB in elderly patients to improve diagnostic accuracy and guide individualized treatment strategies.

Methods

A retrospective analysis of 183 confirmed DR-TB cases (Huai’an Infectious Disease Hospital, June 2013-June 2023) compared chest CT findings (lesion distribution, extent, and morphology) between elderly patients (≥ 60 years) and non-elderly patients (14–59 years).

Results

Key findings reveal that elderly patients demonstrate a higher frequency of extensive lung involvement, with 76% exhibiting lesions in all lung lobes compared to 40.74% in the non-elderly group (P < 0.001). Additionally, the elderly group displayed significantly more pathological features, such as segmental and lobar shadows (61.33% vs. 45.37%, P = 0.033) and lung destruction (22.67% vs. 11.11%, P = 0.035).

Conclusion

The identification of risk factors on chest CT, including the presence of pulmonary and bronchial lesions, highlights the necessity for tailored screening and management strategies for elderly DR-TB patients.