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Background <p>Even though HIV-TB co-infection is an emerging public health issue among migrants in European countries, the number of related articles has shown a decreasing trend.</p> Methods <p>To better estimate the extent of this problem, we analyzed 34 articles reporting both prevalence and odds ratio for HIV-TB co-infection in migrants in European countries. Heterogeneity analysis was conducted to assess potential bias, and a random-effects model was used to calculate the effect size.</p> Results <p>The overall prevalence of HIV-TB co-infection was 9% (95%CI: 7% − 11%) in foreign-born individuals, with higher rates observed in specific subgroups: 14% (95%CI: 5% − 33%) in those from Sub-Saharan Africa, which is higher than the overall average, and 4% (95%CI: 2% − 7%) in those from Latin America, which is lower than the overall average. Compared to the native-born European population, foreign-born individuals had a twofold increased risk of HIV-TB co-infection, with a threefold increased risk for those from Sub-Saharan Africa.</p> Conclusions <p>Our meta-analysis results highlight the disproportionate burden of HIV-TB co-infection among foreign-born people in Europe, particularly those from Sub-Saharan Africa.</p>

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HIV and tuberculosis co-infection in non-European migrants in Europe: a systematic review and meta-analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年10月21日

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  • Domenico Benvenuto,
  • Elena Raffetti,
  • Giancarlo Ceccarelli,
  • Pierluigi Francesco Salvo,
  • Simona Di Giambenedetto,
  • Roberto Cauda,
  • Massimo Ciccozzi,
  • Carlo Torti,
  • Anna Mia Ekström

摘要

Background

Even though HIV-TB co-infection is an emerging public health issue among migrants in European countries, the number of related articles has shown a decreasing trend.

Methods

To better estimate the extent of this problem, we analyzed 34 articles reporting both prevalence and odds ratio for HIV-TB co-infection in migrants in European countries. Heterogeneity analysis was conducted to assess potential bias, and a random-effects model was used to calculate the effect size.

Results

The overall prevalence of HIV-TB co-infection was 9% (95%CI: 7% − 11%) in foreign-born individuals, with higher rates observed in specific subgroups: 14% (95%CI: 5% − 33%) in those from Sub-Saharan Africa, which is higher than the overall average, and 4% (95%CI: 2% − 7%) in those from Latin America, which is lower than the overall average. Compared to the native-born European population, foreign-born individuals had a twofold increased risk of HIV-TB co-infection, with a threefold increased risk for those from Sub-Saharan Africa.

Conclusions

Our meta-analysis results highlight the disproportionate burden of HIV-TB co-infection among foreign-born people in Europe, particularly those from Sub-Saharan Africa.