Scholarlink

Background <p>Hepatitis C viral infection is curable, yet only about one-third of identified cases have been cleared nationally. We evaluated determinants of treatment completion in a sample of newly reported hepatitis C cases among Los Angeles County residents.</p> Methods <p>Using information from the Los Angeles County Hepatitis C Case Registry, we contacted reported hepatitis C ribonucleic acid (RNA) positive cases diagnosed from January 2021 through April 2022. We used Pearson’s Chi-Square Tests and multivariable logistic regression to identify demographic and clinical characteristics associated with self-reported hepatitis C virus treatment completion.</p> Results <p>Among 2,992 reported RNA-positive cases, 619 (21%) were successfully contacted. Among those, most respondents were untreated (72%), male (65%), and tested by primary care providers (50%). Individuals 30–44 years old had 2.9 (95% CI: 1.1, 7.4) times the odds of having completed treatment during initial contact compared to 18–29 year-olds, adjusted for ordering provider type, race/ethnicity, health insurance type, and symptom status. Respondents tested by specialists had 1.8 (95% CI: 1.2, 2.8) times the odds of completing treatment compared to those tested by primary care providers. Respondents who reported symptoms in the past six months had 0.2 (95% CI: 0.1, 0.4) times the odds of completing treatment compared to respondents with no symptoms. Characteristics of respondents were the same as those diagnosed with hepatitis C in Los Angeles County.</p> Conclusions <p>We verified low hepatitis C treatment completion at the population-level. Those 18–29 years old and diagnosed in primary care were least likely to complete treatment.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Determinants of hepatitis C virus treatment completion among Los Angeles County residents

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年10月21日

查看全文
  • Cassidy Hernandez-Tamayo,
  • Chrysovalantis Stafylis,
  • Lokesh Bhardwaj,
  • Riya K. Shah,
  • Tatiana Becerra,
  • Dara Bruce,
  • Roopkamal Saini,
  • Natalie Saremi,
  • Immanuel Thomas,
  • Krzel Manansala-Tan,
  • Arjun P. Vij,
  • Alison Li,
  • Nathan Sudeep,
  • Jacob Gizamba,
  • Bijan Hosseini,
  • Sabrina Navarro,
  • Sofia Ufret-Rivera,
  • Albert J. Farias,
  • Jeffrey D. Klausner

摘要

Background

Hepatitis C viral infection is curable, yet only about one-third of identified cases have been cleared nationally. We evaluated determinants of treatment completion in a sample of newly reported hepatitis C cases among Los Angeles County residents.

Methods

Using information from the Los Angeles County Hepatitis C Case Registry, we contacted reported hepatitis C ribonucleic acid (RNA) positive cases diagnosed from January 2021 through April 2022. We used Pearson’s Chi-Square Tests and multivariable logistic regression to identify demographic and clinical characteristics associated with self-reported hepatitis C virus treatment completion.

Results

Among 2,992 reported RNA-positive cases, 619 (21%) were successfully contacted. Among those, most respondents were untreated (72%), male (65%), and tested by primary care providers (50%). Individuals 30–44 years old had 2.9 (95% CI: 1.1, 7.4) times the odds of having completed treatment during initial contact compared to 18–29 year-olds, adjusted for ordering provider type, race/ethnicity, health insurance type, and symptom status. Respondents tested by specialists had 1.8 (95% CI: 1.2, 2.8) times the odds of completing treatment compared to those tested by primary care providers. Respondents who reported symptoms in the past six months had 0.2 (95% CI: 0.1, 0.4) times the odds of completing treatment compared to respondents with no symptoms. Characteristics of respondents were the same as those diagnosed with hepatitis C in Los Angeles County.

Conclusions

We verified low hepatitis C treatment completion at the population-level. Those 18–29 years old and diagnosed in primary care were least likely to complete treatment.