Aim <p>The impact of sarcopenia on Manual Dexterity (MD) among older adults residing in long-term care settings (LTCS) is understudied. Hence, the objective is to compare MD using the Purdue Pegboard Test (PPT) among older adults with and without sarcopenia.</p> Methods <p>A cross-sectional study was conducted in seven LTCS, and older adults were selected per the criteria decided a priori. Sarcopenia was evaluated through muscle mass, muscle strength, and physical performance using the Asian Working Group for Sarcopenia (AWGS) 2019 criteria, and MD was assessed using PPT.</p> Results <p>Ninety-six older adults were included, with 83 identified as sarcopenic and 13 as non-sarcopenic. Sarcopenic participants exhibited significantly lower scores in PPT, ranging from 1.34 to 4.00&#xa0;s across various sub-tasks, compared to non-sarcopenic participants.</p> Conclusion <p>Sarcopenia significantly affects MD, with a decline of 12% to 33.9% in various dexterity tasks.</p>