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Background <p>Gastrointestinal (GI) disorders represent a major public health concern, yet data from the UAE remain limited, particularly regarding histopathological trends. This study aimed to characterize the epidemiological spectrum and distribution of GI disorders reported to a tertiary care pathology center over a ten-year period. Histopathology-based surveillance offers unique insight into tissue-level patterns often missed by clinical registries.</p> Methods <p>A retrospective, record-based analysis of 12,688 GI-related histopathology reports was conducted from Thumbay Laboratories, UAE (2013–2023). Data was extracted using a structured checklist and analyzed in SPSS v29. Descriptive statistics and inferential tests were applied (<i>p</i> &lt; 0.05).</p> Results <p>Of the 12,688 cases, 67.5% were male and 32.5% female (<i>p</i> &lt; 0.001). Most patients were aged 21–40 years (60.3%). The stomach (29.6%), large intestine (21.2%), and appendix (20.4%) were the most affected organs. Gastritis (27.3%), intestinal conditions (20.6%), and appendicitis (20.0%) predominated. Males showed higher rates of gastritis and appendicitis, while cholecystitis was more common in females (21.4%). Appendicitis was dominant in those &lt; 20 years (60.1%), while neoplasms and gastritis were more prevalent in older adults (≥ 61 years; <i>p</i> &lt; 0.001).</p> Conclusion <p>This study provides a decade-long overview of GI pathology trends in the UAE. The findings highlight age- and sex-specific patterns and support future research integrating clinical and demographic data to inform targeted public health strategies.</p>

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Epidemiological and histopathological spectrum of gastrointestinal tract disorders: a decade of records from the UAE

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年9月29日

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  • Preetha J Shetty,
  • Prasanna Appiya Premvignesh,
  • Sana Imadeddin Albaghdadi,
  • Latifa Nabeel Alsaad,
  • Sunil Kumar Bylappa,
  • Jayadevan Sreedharan,
  • Jayakumary Muttappallymyalil

摘要

Background

Gastrointestinal (GI) disorders represent a major public health concern, yet data from the UAE remain limited, particularly regarding histopathological trends. This study aimed to characterize the epidemiological spectrum and distribution of GI disorders reported to a tertiary care pathology center over a ten-year period. Histopathology-based surveillance offers unique insight into tissue-level patterns often missed by clinical registries.

Methods

A retrospective, record-based analysis of 12,688 GI-related histopathology reports was conducted from Thumbay Laboratories, UAE (2013–2023). Data was extracted using a structured checklist and analyzed in SPSS v29. Descriptive statistics and inferential tests were applied (p < 0.05).

Results

Of the 12,688 cases, 67.5% were male and 32.5% female (p < 0.001). Most patients were aged 21–40 years (60.3%). The stomach (29.6%), large intestine (21.2%), and appendix (20.4%) were the most affected organs. Gastritis (27.3%), intestinal conditions (20.6%), and appendicitis (20.0%) predominated. Males showed higher rates of gastritis and appendicitis, while cholecystitis was more common in females (21.4%). Appendicitis was dominant in those < 20 years (60.1%), while neoplasms and gastritis were more prevalent in older adults (≥ 61 years; p < 0.001).

Conclusion

This study provides a decade-long overview of GI pathology trends in the UAE. The findings highlight age- and sex-specific patterns and support future research integrating clinical and demographic data to inform targeted public health strategies.