Scholarlink

Background <p>Colonoscopy withdrawal time is recognized as a key factor influencing the adenoma detection rate (ADR). Current clinical guidelines recommend a minimum colonoscopy withdrawal time of 6&#xa0;min. However, the optimal withdrawal time for unsedated colonoscopy in elderly patients and its impact on ADR remain uncertain.</p> Methods <p>In this retrospective multicenter study, we collected the withdrawal time (excluding bowel cleansing and polyp resection time) of unsedated colonoscopy in elderly patients, to analyze the relationship between withdrawal time in 1-minute increments and ADR, and the effect of withdrawal time &gt; 8&#xa0;min compared with withdrawal time ≤ 8&#xa0;min on ADR. Multivariate linear regression analysis was employed to assess the optimal withdrawal time influencing ADR.</p> Results <p>A total of 1119 samples (mean age, 70.32 ± 7.17 years; 57.28% male) were included in the analysis, with a median withdrawal time of 9&#xa0;min (interquartile range [IQR], 7–13). The ADR was highest at a withdrawal time of 8&#xa0;min (67.02%), while the adenocarcinoma detection rate (ACDR) peaked at a withdrawal time of 8&#xa0;min (17.02%). In addition, patients with withdrawal time &gt; 8&#xa0;min exhibited a higher ADR than those with ≤ 8&#xa0;min (odds ratio (OR), 1.63; 95% confidence interval (CI), 1.28–2.06; <i>P</i> &lt; 0.001).</p> Conclusions <p>This retrospective multicenter study demonstrates that in elderly patients with contraindications to sedation, achieving a minimum withdrawal time of 8&#xa0;min during unsedated colonoscopy is critical for optimizing ADR.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Impact of withdrawal time on the adenoma detection rate in elderly patients during unsedated colonoscopy: a retrospective multicenter study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年9月26日

查看全文
  • Fu-qiang Liu,
  • Ying-hao He,
  • Han Yan,
  • Jin-wen Liao,
  • Wen-juan Ding,
  • Yu-ting Huang,
  • Zhi-qiang Du,
  • Xiang-rong Zhou,
  • Zheng Jiang

摘要

Background

Colonoscopy withdrawal time is recognized as a key factor influencing the adenoma detection rate (ADR). Current clinical guidelines recommend a minimum colonoscopy withdrawal time of 6 min. However, the optimal withdrawal time for unsedated colonoscopy in elderly patients and its impact on ADR remain uncertain.

Methods

In this retrospective multicenter study, we collected the withdrawal time (excluding bowel cleansing and polyp resection time) of unsedated colonoscopy in elderly patients, to analyze the relationship between withdrawal time in 1-minute increments and ADR, and the effect of withdrawal time > 8 min compared with withdrawal time ≤ 8 min on ADR. Multivariate linear regression analysis was employed to assess the optimal withdrawal time influencing ADR.

Results

A total of 1119 samples (mean age, 70.32 ± 7.17 years; 57.28% male) were included in the analysis, with a median withdrawal time of 9 min (interquartile range [IQR], 7–13). The ADR was highest at a withdrawal time of 8 min (67.02%), while the adenocarcinoma detection rate (ACDR) peaked at a withdrawal time of 8 min (17.02%). In addition, patients with withdrawal time > 8 min exhibited a higher ADR than those with ≤ 8 min (odds ratio (OR), 1.63; 95% confidence interval (CI), 1.28–2.06; P < 0.001).

Conclusions

This retrospective multicenter study demonstrates that in elderly patients with contraindications to sedation, achieving a minimum withdrawal time of 8 min during unsedated colonoscopy is critical for optimizing ADR.