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Background <p>In Europe around 40% of people aged ≥ 65 years are affected by multiple non-communicable chronic diseases (NCDs). The Comprehensive Geriatric Assessment (CGA) showed its usefulness in early identifying healthcare needs of older people with NCDs to develop a care plan to meet these needs. PrimaCare_P3 study aims at assessing healthcare needs of older people referring to their general practitioners (GPs) to plan a personalised prevention programme (PPP) based on the results of the CGA-based short version of the Multidimensional Prognostic Index (BRIEF-MPI).</p> Methods <p>612 participants with at least one NCDs were included in the intervention group (IG) by twenty GPs from four geographical areas. Functional, cognitive, nutritional, social and co-habitation conditions, co-morbidity, polytherapy, and vaccination status were assessed. Following the CGA-based BRIEF-MPI assessment, participants were provided with a PPP, consisting of targeted indications and interventions including prescribed specialistic examinations, if needed.</p> Results <p>Polytherapy and nutritional status were the most impaired domains with 59% of participants showing severe polypharmacy requiring a deprescribing strategy on GP’s judgement while 25% of participants being malnourished or overweight/obese. Moreover, 22% of participants showed cognitive impairment requiring intervention, 18.5% were at risk of social isolation and/or loneliness, and 16.5% had some form of functional impairments in activities of daily living. Missing vaccinations according to the National Vaccination Prevention Plan (PNPV) were anti-influenza (34%), anti-COVID-19 (45%), anti-pneumococcus (74%), anti-herpes zoster (89%).</p> Conclusions <p>These data suggest that the CGA-based BRIEF-MPI assessment could effectively identify older adults’ healthcare needs to be addressed with a PPP in general practice setting.</p> Trial registration <p>Registered on clinicaltrials.gov, NCT06224556, 05-01-2024.</p>

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Usefulness of the BRIEF-Multidimensional Prognostic Index (BRIEF-MPI) to identify older adults’ healthcare needs to be addressed with a Personalized Prevention Program in general practice: preliminary data from the PrimaCare_P3 study

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  • 发表日期：

    2025年10月27日

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  • Alberto Pilotto,
  • Wanda Morganti,
  • Emanuele Seminerio,
  • Eleonora Lacorte,
  • Carlo Custodero,
  • Nicola Veronese,
  • Peter Fielding,
  • Carolina Massone,
  • Paola Piscopo,
  • Elisa Fabrizi,
  • Patrizia Lorenzini,
  • Alberto Magni,
  • Gaetano Piccinocchi,
  • Carlo Ignazzi,
  • Lorenza Busco,
  • Mario Barbagallo,
  • Cesare Massone,
  • Pierangelo Lora Aprile,
  • Nicola Vanacore

摘要

Background

In Europe around 40% of people aged ≥ 65 years are affected by multiple non-communicable chronic diseases (NCDs). The Comprehensive Geriatric Assessment (CGA) showed its usefulness in early identifying healthcare needs of older people with NCDs to develop a care plan to meet these needs. PrimaCare_P3 study aims at assessing healthcare needs of older people referring to their general practitioners (GPs) to plan a personalised prevention programme (PPP) based on the results of the CGA-based short version of the Multidimensional Prognostic Index (BRIEF-MPI).

Methods

612 participants with at least one NCDs were included in the intervention group (IG) by twenty GPs from four geographical areas. Functional, cognitive, nutritional, social and co-habitation conditions, co-morbidity, polytherapy, and vaccination status were assessed. Following the CGA-based BRIEF-MPI assessment, participants were provided with a PPP, consisting of targeted indications and interventions including prescribed specialistic examinations, if needed.

Results

Polytherapy and nutritional status were the most impaired domains with 59% of participants showing severe polypharmacy requiring a deprescribing strategy on GP’s judgement while 25% of participants being malnourished or overweight/obese. Moreover, 22% of participants showed cognitive impairment requiring intervention, 18.5% were at risk of social isolation and/or loneliness, and 16.5% had some form of functional impairments in activities of daily living. Missing vaccinations according to the National Vaccination Prevention Plan (PNPV) were anti-influenza (34%), anti-COVID-19 (45%), anti-pneumococcus (74%), anti-herpes zoster (89%).

Conclusions

These data suggest that the CGA-based BRIEF-MPI assessment could effectively identify older adults’ healthcare needs to be addressed with a PPP in general practice setting.

Trial registration

Registered on clinicaltrials.gov, NCT06224556, 05-01-2024.