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Background <p>Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is frequently accompanied by anxiety and depressive symptoms, which may affect quality of life. While catheter ablation (CA) is an established therapy for AF, data comparing emotional distress burden prior to first-time vs. redo CA procedures remain limited.</p> Aim <p>To compare pre-procedural anxiety and depressive symptoms in patients undergoing first-time AF/atypical atrial flutter CA vs. those undergoing redo AF/atypical atrial flutter CA.</p> Methods <p>This prospective observational study included patients with AF or atypical atrial flutter scheduled for CA (first-time or redo) between January 2024 and May 2025. Anxiety and depressive symptoms were assessed one day prior to the CA using the Hospital Anxiety and Depression Scale (HADS).</p> Results <p>Overall, 112 patients who underwent first-time CA and 49 patients who underwent redo CA were included. Most baseline characteristics were similar between groups; however, redo CA patients had a higher prevalence of persistent AF and prior stroke and higher CHA₂DS₂-VA scores. Patients scheduled for first-time (vs. redo) CA had significantly higher emotional distress. Median HADS depression and anxiety scores were significantly higher in the first-time CA group compared with the redo CA group (10 [9–11] vs. 2 [1–5], <i>p</i> &lt; 0.001 and 13 [11.5–14] vs. 5 [2–9], <i>p</i> &lt; 0.001; respectively. Distributional analyses demonstrated a consistent shift of the HADS-A and HADS-D score distributions toward higher values in the first-time CA group, supported by large non-parametric effect sizes. After adjustment for persistent AF, diabetes mellitus, and prior stroke, first-time CA remained associated with a higher burden of anxiety and depressive symptoms compared with redo CA patients. Persistent AF was associated with lower odds of depressive symptoms.</p> Conclusions <p>Patients undergoing first-time AF CA experience higher anxiety and depressive symptom burden than those undergoing redo CA.</p>

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Emotional distress in patients before first-time and redo catheter ablation for atrial fibrillation

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年8月5日

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  • Maja Jabłońska,
  • Bartosz Krzowski,
  • Wojciech Olszewski,
  • Michał Gawlik,
  • Alicja Skrobucha,
  • Mateusz Wawrzeńczyk,
  • Kacper Rutkowski,
  • Julia Szydlik,
  • Weronika Słomiana,
  • Monika Gawałko,
  • Michał Peller,
  • Piotr Lodziński,
  • Marcin Grabowski,
  • Paweł Balsam

摘要

Background

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is frequently accompanied by anxiety and depressive symptoms, which may affect quality of life. While catheter ablation (CA) is an established therapy for AF, data comparing emotional distress burden prior to first-time vs. redo CA procedures remain limited.

Aim

To compare pre-procedural anxiety and depressive symptoms in patients undergoing first-time AF/atypical atrial flutter CA vs. those undergoing redo AF/atypical atrial flutter CA.

Methods

This prospective observational study included patients with AF or atypical atrial flutter scheduled for CA (first-time or redo) between January 2024 and May 2025. Anxiety and depressive symptoms were assessed one day prior to the CA using the Hospital Anxiety and Depression Scale (HADS).

Results

Overall, 112 patients who underwent first-time CA and 49 patients who underwent redo CA were included. Most baseline characteristics were similar between groups; however, redo CA patients had a higher prevalence of persistent AF and prior stroke and higher CHA₂DS₂-VA scores. Patients scheduled for first-time (vs. redo) CA had significantly higher emotional distress. Median HADS depression and anxiety scores were significantly higher in the first-time CA group compared with the redo CA group (10 [9–11] vs. 2 [1–5], p < 0.001 and 13 [11.5–14] vs. 5 [2–9], p < 0.001; respectively. Distributional analyses demonstrated a consistent shift of the HADS-A and HADS-D score distributions toward higher values in the first-time CA group, supported by large non-parametric effect sizes. After adjustment for persistent AF, diabetes mellitus, and prior stroke, first-time CA remained associated with a higher burden of anxiety and depressive symptoms compared with redo CA patients. Persistent AF was associated with lower odds of depressive symptoms.

Conclusions

Patients undergoing first-time AF CA experience higher anxiety and depressive symptom burden than those undergoing redo CA.