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Introduction <p>Currently, the interaction between heart failure with preserved ejection fraction (HFpEF) and obesity is discussed. As part of a complex echocardiographic examination, the two-dimensional speckle tracking (2D-STE) method is a significant tool for assessing dysfunction of the left atrium. Our study aimed to compare left atrial function using the 2D-STE in patients with class III obesity and a control group.</p> Methods <p>This was an observational, prospective, pilot /preliminary/ study that enrolled 20 patients with class III obesity (Body mass index (BMI) &gt; 40&#xa0;kg/m²) and a group of nineteen healthy individuals with a BMI of 20–25&#xa0;kg/m² as controls. The following parameters were observed: Reservoir Left Atrial Strain (R-LAS), Conduit Time (CT-LAS), and Contractile Displacement (CD-LAS).</p> Results <p>The study patient group included sixteen women and four men (average age 42.4 years, ranging 19–63). The mean BMI was 47.69 ± 8.86&#xa0;kg/m². The control group was created from fifteen women and four men (average age 27.2 ± 3.7 years, average BMI 22.48&#xa0;kg/m²). The study found significant differences in R-LAS (29.9 ± 7.0 vs. 45.0 ± 11.7;<i>p</i> &lt; 0.001) and CT-LAS (-16.8 ± 5.89 vs. -29.7 ± 8.71;<i>p</i> &lt; 0.001) between patients with class III obesity and controls. No significant difference was seen in the remaining studied parameter /CD-LAS/ (-13.2 ± 4.77 vs. -15.1 ± 6.28;<i>p</i> = 0.305).</p> Conclusion <p>The R-LAS and CT-LAS were significantly changed (reduced) in patients with class III obesity compared to the controls.</p>

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Left atrial function in class III obesity: a pilot study using two-dimensional speckle tracking echocardiography

  • 期刊论文

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  • 发表日期：

    2026年3月6日

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  • Peter Tudík,
  • Jakub Jurica,
  • Martin Jozef Péč,
  • Boris Focko,
  • Zuzana Miertová,
  • Andrej Miert,
  • Lucia Kubíková,
  • Norbert Nagy,
  • Patrik Lecký,
  • Ivana Ságová,
  • Tomáš Bolek,
  • Marianna Barbierik Vachalcová,
  • Marián Mokáň,
  • Matej Samoš

摘要

Introduction

Currently, the interaction between heart failure with preserved ejection fraction (HFpEF) and obesity is discussed. As part of a complex echocardiographic examination, the two-dimensional speckle tracking (2D-STE) method is a significant tool for assessing dysfunction of the left atrium. Our study aimed to compare left atrial function using the 2D-STE in patients with class III obesity and a control group.

Methods

This was an observational, prospective, pilot /preliminary/ study that enrolled 20 patients with class III obesity (Body mass index (BMI) > 40 kg/m²) and a group of nineteen healthy individuals with a BMI of 20–25 kg/m² as controls. The following parameters were observed: Reservoir Left Atrial Strain (R-LAS), Conduit Time (CT-LAS), and Contractile Displacement (CD-LAS).

Results

The study patient group included sixteen women and four men (average age 42.4 years, ranging 19–63). The mean BMI was 47.69 ± 8.86 kg/m². The control group was created from fifteen women and four men (average age 27.2 ± 3.7 years, average BMI 22.48 kg/m²). The study found significant differences in R-LAS (29.9 ± 7.0 vs. 45.0 ± 11.7;p < 0.001) and CT-LAS (-16.8 ± 5.89 vs. -29.7 ± 8.71;p < 0.001) between patients with class III obesity and controls. No significant difference was seen in the remaining studied parameter /CD-LAS/ (-13.2 ± 4.77 vs. -15.1 ± 6.28;p = 0.305).

Conclusion

The R-LAS and CT-LAS were significantly changed (reduced) in patients with class III obesity compared to the controls.