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Objective <p>To evaluate the efficacy of ultrasound-guided thyroid cartilage plane block (TCPB) on postoperative sore throat (POST) in patients undergoing suspension laryngoscopy vocal cord polypectomy (SLVCP).</p> Methods <p>Ninety patients scheduled for elective SLVCP were randomized to either the TCPB group (general anesthesia + ultrasound-guided TCPB) or the C group (conventional GA), with 45 patients in each. The primary outcome was the incidence of POST at 2&#xa0;h after extubation. Secondary outcomes included the incidence and severity of POST at 0.5, 2, 6, 12, and 24&#xa0;h after extubation; the incidence and severity of hoarseness at 0.5, 2, 6, 12, and 24&#xa0;h after extubation; and cough response during emergence.</p> Results <p>The incidence of POST was significantly higher in the C group compared to the TCPB group at 0.5&#xa0;h (93% vs. 67%, RR = 0.20, 95% CI [0.06–0.64]; <i>P</i> = 0.003), 2&#xa0;h (78% vs. 47%, RR = 0.42, 95% CI [0.23–0.77]; <i>P</i> = 0.004), and 6&#xa0;h (64% vs. 27%, RR = 0.49, 95% CI [0.32–0.77]; <i>P</i> = 0.001) after extubation. No significant difference in the incidence and severity of hoarseness between the groups at any time point. During extubation, the incidence of cough response in the C group was 60%, significantly higher than the 20% in the TCPB group (RR = 0.50, 95% CI [0.34–0.74]; <i>P</i> = 0.001).</p> Conclusion <p>Ultrasound-guided TCPB significantly reduces the incidence and severity of POST and cough response in SLVCP patients.</p> Trial registration <p>This trial was registered in the Chinese Clinical Trial Registry (ChiCTR2500100227) on April 7, 2025 (<a href="https://www.chictr.org.cn/">https://www.chictr.org.cn/</a>).</p>

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Effect of ultrasound-guided thyroid cartilage plane block on postoperative sore throat in patients undergoing vocal cord polypectomy under suspension laryngoscopy: a randomized controlled trial

  • 期刊论文

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  • 发表日期：

    2026年6月29日

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  • Fang Huang,
  • Yufeng Zhang,
  • Zenghua Cai,
  • Jinbao Wang,
  • Songchao Xu,
  • Huili Li,
  • Yun Wang

摘要

Objective

To evaluate the efficacy of ultrasound-guided thyroid cartilage plane block (TCPB) on postoperative sore throat (POST) in patients undergoing suspension laryngoscopy vocal cord polypectomy (SLVCP).

Methods

Ninety patients scheduled for elective SLVCP were randomized to either the TCPB group (general anesthesia + ultrasound-guided TCPB) or the C group (conventional GA), with 45 patients in each. The primary outcome was the incidence of POST at 2 h after extubation. Secondary outcomes included the incidence and severity of POST at 0.5, 2, 6, 12, and 24 h after extubation; the incidence and severity of hoarseness at 0.5, 2, 6, 12, and 24 h after extubation; and cough response during emergence.

Results

The incidence of POST was significantly higher in the C group compared to the TCPB group at 0.5 h (93% vs. 67%, RR = 0.20, 95% CI [0.06–0.64]; P = 0.003), 2 h (78% vs. 47%, RR = 0.42, 95% CI [0.23–0.77]; P = 0.004), and 6 h (64% vs. 27%, RR = 0.49, 95% CI [0.32–0.77]; P = 0.001) after extubation. No significant difference in the incidence and severity of hoarseness between the groups at any time point. During extubation, the incidence of cough response in the C group was 60%, significantly higher than the 20% in the TCPB group (RR = 0.50, 95% CI [0.34–0.74]; P = 0.001).

Conclusion

Ultrasound-guided TCPB significantly reduces the incidence and severity of POST and cough response in SLVCP patients.

Trial registration

This trial was registered in the Chinese Clinical Trial Registry (ChiCTR2500100227) on April 7, 2025 (https://www.chictr.org.cn/).