Scholarlink

Objective <p>To explore the value of the Vasoactive-Inotropic Score (VIS) in evaluating the prognosis of patients admitted to the ICU after noncardiac surgical operations.</p> Methods <p>A retrospective analysis was conducted on 3,365 post-noncardiac surgical patients admitted to the Department of Critical Care Medicine, The First Affiliated Hospital of Sun Yat-sen University, from January 2018 to June 2022. The VIS was calculated based on the maximum and average doses of vasoactive and inotropic agents administered within the first 24&#xa0;h after noncardiac surgery. Patients were divided into five groups according to VIS levels: 0–5, 6–15, 16–30, 31–45, and &gt; 45 points.</p> Results <p>The primary outcome was 28-day mortality. The mean 24-h maximum VIS of post-noncardiac surgical ICU patients was 1.2, with over half of the patients having a VIS below 5 points. Mortality in patients with higher VIS was significantly higher than in those with lower VIS, with the mortality rates of the five VIS groups being 7.5%, 9.4%, 12.1%, 17.2%, and 33.8%, respectively. Kaplan–Meier survival curves showed that patients with a VIS &gt; 45 had poorer survival rates. The incidence of infection and sepsis increased with higher VIS. Multivariate logistic regression analysis identified a 24-h maximum VIS &gt; 45 was an independent risk factor for 28-day mortality. VIS yielded an AUC of 0.744 for predicting ICU mortality and 0.683 for predicting 28-day mortality. In short-term prognosis assessment, the predictive value of VIS was better than the Sequential Organ Failure Assessment (SOFA) score and serum lactate level.</p> Conclusions <p>Adult post-noncardiac surgical ICU patients have a high incidence of infection and poor outcomes. A higher VIS robustly predicts adverse postoperative outcomes, with independent prognostic value in this Chinese cohort. Though not supplanting established tools (e.g., Acute Physiology and Chronic Health Evaluation II [APACHE II], SOFA), VIS serves as a complementary indicator, providing additional real-time hemodynamic insights. Larger prospective studies are needed to verify whether VIS-guided interventions improve patient outcomes.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Assessment of the vasoactive-inotropic score in prognostic evaluation of critical patients following noncardiac surgery: a retrospective, observational study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月9日

查看全文
  • Rongjie Jiang,
  • Xiaodong Song,
  • Huan Ma,
  • Shuhe Li,
  • Ka Yin Lui,
  • Xiaoguang Hu,
  • Yanping Zhu,
  • Changjie Cai,
  • Zhaoxia Tang

摘要

Objective

To explore the value of the Vasoactive-Inotropic Score (VIS) in evaluating the prognosis of patients admitted to the ICU after noncardiac surgical operations.

Methods

A retrospective analysis was conducted on 3,365 post-noncardiac surgical patients admitted to the Department of Critical Care Medicine, The First Affiliated Hospital of Sun Yat-sen University, from January 2018 to June 2022. The VIS was calculated based on the maximum and average doses of vasoactive and inotropic agents administered within the first 24 h after noncardiac surgery. Patients were divided into five groups according to VIS levels: 0–5, 6–15, 16–30, 31–45, and > 45 points.

Results

The primary outcome was 28-day mortality. The mean 24-h maximum VIS of post-noncardiac surgical ICU patients was 1.2, with over half of the patients having a VIS below 5 points. Mortality in patients with higher VIS was significantly higher than in those with lower VIS, with the mortality rates of the five VIS groups being 7.5%, 9.4%, 12.1%, 17.2%, and 33.8%, respectively. Kaplan–Meier survival curves showed that patients with a VIS > 45 had poorer survival rates. The incidence of infection and sepsis increased with higher VIS. Multivariate logistic regression analysis identified a 24-h maximum VIS > 45 was an independent risk factor for 28-day mortality. VIS yielded an AUC of 0.744 for predicting ICU mortality and 0.683 for predicting 28-day mortality. In short-term prognosis assessment, the predictive value of VIS was better than the Sequential Organ Failure Assessment (SOFA) score and serum lactate level.

Conclusions

Adult post-noncardiac surgical ICU patients have a high incidence of infection and poor outcomes. A higher VIS robustly predicts adverse postoperative outcomes, with independent prognostic value in this Chinese cohort. Though not supplanting established tools (e.g., Acute Physiology and Chronic Health Evaluation II [APACHE II], SOFA), VIS serves as a complementary indicator, providing additional real-time hemodynamic insights. Larger prospective studies are needed to verify whether VIS-guided interventions improve patient outcomes.