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Background <p>Patients with multiple rib fractures (MRFs) often experience severe postoperative pain. The parascapular sub-iliocostalis plane (PSIP) block holds promise as an effective method for analgesia, warranting further investigation and validation.</p> Methods <p>In this double-masked randomized trial, eligible MRF patients underwent surgery and were allocated to receive either preoperative PSIP block (intervention) or standard care (control). Postoperative outcomes including pain trajectories (serial VAS assessments), analgesic consumption, hemodynamic stability, recovery metrics (QoR-15), and adverse events were systematically evaluated. Statistical analyses adhered to intention-to-treat principles.</p> Results <p>The AUC<sub>0.5−24</sub> of VAS<sub>pain</sub> curves of Group PSIP was lower (<i>P</i> = 0.016). The VAS<sub>pain</sub> of Group PSIP were lower at 0.5&#xa0;h, 2&#xa0;h, 6&#xa0;h, 12&#xa0;h, and 24&#xa0;h after the extubation (<i>P</i> &lt; 0.001, 0.005, &lt; 0.001, 0.020, 0.029). There was a decrease in VAS<sub>pain</sub> in Group PSIP after blocking (<i>P</i> &lt; 0.001). Patients in Group PSIP required a lesser amount of analgesics within the initial twenty-four hours following surgery (<i>P</i> = 0.026). Group C had a significantly earlier use of analgesics (<i>P</i> &lt; 0.001). At the time of skin incision, fracture reduction, suture and after extubation, Group PSIP had a lower MAP (<i>P</i> = 0.002, &lt; 0.001, 0.003, 0.001) and AUC of MAP curves (<i>P</i> = 0.039). The Group PSIP exhibited lower Ricker scores in PACU, along with shorter observation times as well (<i>P</i> = 0.005, 0.046). The severity of PONV within 24&#xa0;h post-surgery in the Group PSIP was also lower (<i>P</i> = 0.013). Moreover, at the 24&#xa0;h post-surgery, the QoR-15 score was higher in Group PSIP (<i>P</i> = 0.025).</p> Conclusions <p>The PSIP block demonstrated efficacy in managing postoperative pain in patients with MRFs, mitigating intraoperative hemodynamic fluctuations and agitation during resuscitation, and enhancing short-term recovery outcomes following surgery.</p>

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Parascapular sub-iliocostalis plane block for postoperative analgesia in patients with multiple rib fractures: a randomized controlled trial

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年7月1日

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  • Qiji Ju,
  • Ping Li,
  • Long Zhang,
  • Liangguang Zhang,
  • Guanyi Liu,
  • Liyong Yuan,
  • Miao Zhu

摘要

Background

Patients with multiple rib fractures (MRFs) often experience severe postoperative pain. The parascapular sub-iliocostalis plane (PSIP) block holds promise as an effective method for analgesia, warranting further investigation and validation.

Methods

In this double-masked randomized trial, eligible MRF patients underwent surgery and were allocated to receive either preoperative PSIP block (intervention) or standard care (control). Postoperative outcomes including pain trajectories (serial VAS assessments), analgesic consumption, hemodynamic stability, recovery metrics (QoR-15), and adverse events were systematically evaluated. Statistical analyses adhered to intention-to-treat principles.

Results

The AUC0.5−24 of VASpain curves of Group PSIP was lower (P = 0.016). The VASpain of Group PSIP were lower at 0.5 h, 2 h, 6 h, 12 h, and 24 h after the extubation (P < 0.001, 0.005, < 0.001, 0.020, 0.029). There was a decrease in VASpain in Group PSIP after blocking (P < 0.001). Patients in Group PSIP required a lesser amount of analgesics within the initial twenty-four hours following surgery (P = 0.026). Group C had a significantly earlier use of analgesics (P < 0.001). At the time of skin incision, fracture reduction, suture and after extubation, Group PSIP had a lower MAP (P = 0.002, < 0.001, 0.003, 0.001) and AUC of MAP curves (P = 0.039). The Group PSIP exhibited lower Ricker scores in PACU, along with shorter observation times as well (P = 0.005, 0.046). The severity of PONV within 24 h post-surgery in the Group PSIP was also lower (P = 0.013). Moreover, at the 24 h post-surgery, the QoR-15 score was higher in Group PSIP (P = 0.025).

Conclusions

The PSIP block demonstrated efficacy in managing postoperative pain in patients with MRFs, mitigating intraoperative hemodynamic fluctuations and agitation during resuscitation, and enhancing short-term recovery outcomes following surgery.