Scholarlink

Background <p>The composition of fatty acids, particularly the content of unsaturated fatty acids (UFA), is closely related to meat quality and flavor in ducks.</p> Result <p>In this study, 38 fatty acids were detected in the breast muscle of Sansui ducks, yielding 50 distinct fatty acid composition traits. The results showed that the predominant fatty acids were C18:1n-9, C16:0, C18:2n-6, C18:0, and C20:4n-6. Moreover, the breast muscle of Sansui duck was rich in UFA, accounting for 64.01% of the total fatty acids. Genome-wide association analysis (GWAS) identified 158 single nucleotide polymorphisms (SNPs) significantly associated with fatty acid composition traits, which were annotated to 70 protein-coding genes, including <i>LDLRAD3</i>, <i>ACVR1</i>, <i>FGF6</i>, and <i>CASQ2</i>. Additionally, linkage disequilibrium (LD) analysis revealed a candidate region (10,533,318 − 10,546,189&#xa0;bp) on chromosome 14, where <i>NSG2</i> was identified as a key candidate gene influencing C17:1 content. Functional enrichment analysis suggested that pathways such as Adherens junctions and MAPK signaling may play significant roles in fatty acid biosynthesis.</p> Conclusion <p>These findings reveal the genetic structure of fatty acids composition in the breast muscle of Sansui duck, providing strong evidence for understanding the genetic regulatory mechanisms of fatty acid composition.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Genetic loci and key candidate genes associated with fatty acid composition in the breast muscle of Sansui ducks identified through GWAS

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年5月7日

查看全文
  • Yulong Feng,
  • Mengru Xu,
  • Meijuan Li,
  • Yuxi Lu,
  • Guotao Dai,
  • Chengcheng Tian,
  • Yu Zhao,
  • Hehe Liu,
  • Anqi Huang

摘要

Background

The composition of fatty acids, particularly the content of unsaturated fatty acids (UFA), is closely related to meat quality and flavor in ducks.

Result

In this study, 38 fatty acids were detected in the breast muscle of Sansui ducks, yielding 50 distinct fatty acid composition traits. The results showed that the predominant fatty acids were C18:1n-9, C16:0, C18:2n-6, C18:0, and C20:4n-6. Moreover, the breast muscle of Sansui duck was rich in UFA, accounting for 64.01% of the total fatty acids. Genome-wide association analysis (GWAS) identified 158 single nucleotide polymorphisms (SNPs) significantly associated with fatty acid composition traits, which were annotated to 70 protein-coding genes, including LDLRAD3, ACVR1, FGF6, and CASQ2. Additionally, linkage disequilibrium (LD) analysis revealed a candidate region (10,533,318 − 10,546,189 bp) on chromosome 14, where NSG2 was identified as a key candidate gene influencing C17:1 content. Functional enrichment analysis suggested that pathways such as Adherens junctions and MAPK signaling may play significant roles in fatty acid biosynthesis.

Conclusion

These findings reveal the genetic structure of fatty acids composition in the breast muscle of Sansui duck, providing strong evidence for understanding the genetic regulatory mechanisms of fatty acid composition.