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Objective <p><i>Enterobacter</i> species are important nosocomial pathogens, mainly due to multidrug resistance (MDR). This study reports the whole-genome sequences of <i>Enterobacter cloacae</i> H5 and <i>Enterobacter bugandensis</i> H6.</p> Data description <p>Digital DNA-DNA hybridization (dDDH) confirmed species identity: H5 (91.8% with <i>E. cloacae</i> ATCC 13047) and H6 (89.3% with <i>E. bugandensis</i> EB-247). H5 has 46 contigs, 4,867,245&#xa0;bp, GC 54.97%; H6 has 27 contigs, 4,616,569&#xa0;bp, GC 56.05%. Phylogenetic analysis grouped H5 within <i>E. cloacae</i> and H6 within <i>E. bugandensis</i>. Both genomes harbor multiple antimicrobial resistance (AMR) genes. H5 includes β-lactamase CMH-16, FosA2, efflux pumps (oqxA, emrB), and regulators (ramA, baeR, baeS). H6 includes β-lactamase ACT-146, FosA2, efflux pumps (oqxA, emrB, msbA), regulators (baeR, baeS), and target modification gene ArnT. These genomes highlight the clinical significance of these strains and provide essential resources for understanding the genomic basis of antimicrobial resistance in Sudanese <i>Enterobacter</i> isolates.</p>

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Whole-genome sequences of Enterobacter cloacae H5 and Enterobacter bugandensis H6 isolated from patients in Khartoum State, Sudan

  • 期刊论文

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  • 发表日期：

    2026年7月10日

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  • Hiba A. A. Mahgoub,
  • Mogahid M. Elhassan,
  • Hind H. Ahmed,
  • Hisham N. Altyab,
  • Mohamed E. Hamid

摘要

Objective

Enterobacter species are important nosocomial pathogens, mainly due to multidrug resistance (MDR). This study reports the whole-genome sequences of Enterobacter cloacae H5 and Enterobacter bugandensis H6.

Data description

Digital DNA-DNA hybridization (dDDH) confirmed species identity: H5 (91.8% with E. cloacae ATCC 13047) and H6 (89.3% with E. bugandensis EB-247). H5 has 46 contigs, 4,867,245 bp, GC 54.97%; H6 has 27 contigs, 4,616,569 bp, GC 56.05%. Phylogenetic analysis grouped H5 within E. cloacae and H6 within E. bugandensis. Both genomes harbor multiple antimicrobial resistance (AMR) genes. H5 includes β-lactamase CMH-16, FosA2, efflux pumps (oqxA, emrB), and regulators (ramA, baeR, baeS). H6 includes β-lactamase ACT-146, FosA2, efflux pumps (oqxA, emrB, msbA), regulators (baeR, baeS), and target modification gene ArnT. These genomes highlight the clinical significance of these strains and provide essential resources for understanding the genomic basis of antimicrobial resistance in Sudanese Enterobacter isolates.