Occlusive retinal vasculitis associated with intravitreal Faricimab injections

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2024年9月27日

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Felix F. Reichel,
Peter Kiraly,
Roopa Vemala,
Stella Hornby,
Samantha R. De Silva,
M. Dominik Fischer

摘要

Purpose

We describe a case of occlusive vasculitis associated with intravitreal Faricimab (Vabysmo) injections.

Methods

A retrospective case report.

Results

A 52-year old man treated with monthly Faricimab injections for diabetic macula oedema presented with sudden reduced vision, new retinal hemorrhages, significant retinal vascular occlusions and ischemia. After screening for differential diagnoses was unremarkable, the patient was treated with oral and intravitreal steroid therapy under which the occlusive vasculitis was stabilized.

Conclusion

Occlusive vasculitis, though rare, is a potential complication of Faricimab therapy. Comprehensive reporting and large-scale analyses are essential to better understand and manage this adverse event.