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Foscarnet eyedrops for the treatment of refractory herpetic keratitis

  • Caroline C. Awh,
  • Austen N. Knapp,
  • Jeffrey M. Goshe,
  • Craig W. See,
  • Careen Y. Lowder

摘要

Purpose

The purpose of this case series is to describe the clinical course of patients receiving foscarnet eyedrops for the treatment of refractory herpetic keratitis.

Observations

Six patients diagnosed with herpetic keratitis were treated with foscarnet 24 mg/mL (2.4%) eyedrops with resulting improvement in keratitis.

Conclusion

Topical foscarnet may be a safe and effective treatment for herpetic keratitis in conjunction with, or as an alternative to, conventional antiviral therapy. This is an off-label use of foscarnet.