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Background <p>Venous gas embolus secondary to deep soft tissue infection is a rare but potentially fatal condition in emergency settings that requires urgent medical intervention.</p> Case presentation <p>We report a case of a 32-year-old female with an invasive mole undergoing chemotherapy who presented with fever and severe bilateral lower limb pain. Point-of-care ultrasound (POCUS) revealed gas emboli on B-mode and Doppler-mode imaging within the femoral veins and further detected emphysematous changes in adjacent intramuscular and subcutaneous tissues, suggesting critical infection and initiating immediate clinical reassessment. The patient was subsequently confirmed to have severe hypoxemia and sepsis, with computed tomography demonstrating extensive gas-forming lesions, ultimately leading to cardiac arrest despite advanced life support.</p> Conclusion <p>This case highlights the critical role of POCUS in the rapid detection of intravascular gas and deep soft tissue infection in time-critical conditions.</p>

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Silent but lethal: intravenous gas visualized by point-of-care ultrasound

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年2月2日

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  • Yanxiang Wu,
  • Jiayuan Dai,
  • Qing Zhang,
  • Ning Ma

摘要

Background

Venous gas embolus secondary to deep soft tissue infection is a rare but potentially fatal condition in emergency settings that requires urgent medical intervention.

Case presentation

We report a case of a 32-year-old female with an invasive mole undergoing chemotherapy who presented with fever and severe bilateral lower limb pain. Point-of-care ultrasound (POCUS) revealed gas emboli on B-mode and Doppler-mode imaging within the femoral veins and further detected emphysematous changes in adjacent intramuscular and subcutaneous tissues, suggesting critical infection and initiating immediate clinical reassessment. The patient was subsequently confirmed to have severe hypoxemia and sepsis, with computed tomography demonstrating extensive gas-forming lesions, ultimately leading to cardiac arrest despite advanced life support.

Conclusion

This case highlights the critical role of POCUS in the rapid detection of intravascular gas and deep soft tissue infection in time-critical conditions.