Scholarlink

Background <p>Anemia is a common comorbidity among patients with acute heart failure (AHF) and is associated with worse clinical outcomes. However, there is limited data on the effects of anemia in AHF patients in Asian populations. Moreover, the impact of anemia at varying severity levels in patients presenting to the emergency department (ED) is still not well understood.</p> Objectives <p>This study aimed to evaluate the prevalence and severity of anemia, together with its association with clinical outcomes in adult patients with AHF.</p> Methods <p>A retrospective analysis was conducted on 890 adult AHF patients extracted from 100,420 ED visits at Srinagarind Hospital between October 2021 and March 2023. Anemia was classified into three categories: mild (hemoglobin 11.0&#xa0;g/dl to normal), moderate (hemoglobin 8.0–10.9&#xa0;g/dl), and severe (hemoglobin &lt; 8.0&#xa0;g/dl). Patient characteristics, laboratory markers, and outcomes were compared among groups.</p> Results <p>Of the 890 patients, 71% were anemic, with 25% having mild, 51% moderate, and 24% severe anemia. Anemic patients, particularly those with moderate and severe anemia, were older (median age 74 and 71.5 years vs. 64 years for non-anemic, p-value &lt; 0.001) and had higher rates of comorbidities, including chronic kidney disease and diabetes. Severe anemia was associated with worse kidney function (median eGFR 28.9 vs. 62.9 mL/min/1.73&#xa0;m² for non-anemic, p-value &lt; 0.001) and higher initial cardiac troponin T levels (85.8 vs. 39.1 ng/dL, p-value &lt; 0.001). Hospital admission rates increased with anemia severity, with 93% of severely anemic patients being admitted compared to 81% of non-anemic patients. In-hospital mortality was highest in the severe anemia group (8.6%), though this was not statistically significant (p-value = 0.238).</p> Conclusion <p>Anemia is common in patients with AHF, with many exhibiting moderate or severe levels of anemia. Greater severity of anemia correlates with older age, more comorbidities, and higher hospital admission rates, along with a trend toward higher mortality.</p> Clinical trial number <p>Not applicable.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Prevalence of anemia and its association with poor outcomes in acute heart failure patients in northeastern Thailand

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年11月7日

查看全文
  • Praew Kotruchin,
  • Pannita Duangprasat,
  • Thanat Tangpaisarn,
  • Pariwat Phungoen,
  • Thapanawong Mitsungnern,
  • Marturod Buranasakda,
  • Vichai Senthong

摘要

Background

Anemia is a common comorbidity among patients with acute heart failure (AHF) and is associated with worse clinical outcomes. However, there is limited data on the effects of anemia in AHF patients in Asian populations. Moreover, the impact of anemia at varying severity levels in patients presenting to the emergency department (ED) is still not well understood.

Objectives

This study aimed to evaluate the prevalence and severity of anemia, together with its association with clinical outcomes in adult patients with AHF.

Methods

A retrospective analysis was conducted on 890 adult AHF patients extracted from 100,420 ED visits at Srinagarind Hospital between October 2021 and March 2023. Anemia was classified into three categories: mild (hemoglobin 11.0 g/dl to normal), moderate (hemoglobin 8.0–10.9 g/dl), and severe (hemoglobin < 8.0 g/dl). Patient characteristics, laboratory markers, and outcomes were compared among groups.

Results

Of the 890 patients, 71% were anemic, with 25% having mild, 51% moderate, and 24% severe anemia. Anemic patients, particularly those with moderate and severe anemia, were older (median age 74 and 71.5 years vs. 64 years for non-anemic, p-value < 0.001) and had higher rates of comorbidities, including chronic kidney disease and diabetes. Severe anemia was associated with worse kidney function (median eGFR 28.9 vs. 62.9 mL/min/1.73 m² for non-anemic, p-value < 0.001) and higher initial cardiac troponin T levels (85.8 vs. 39.1 ng/dL, p-value < 0.001). Hospital admission rates increased with anemia severity, with 93% of severely anemic patients being admitted compared to 81% of non-anemic patients. In-hospital mortality was highest in the severe anemia group (8.6%), though this was not statistically significant (p-value = 0.238).

Conclusion

Anemia is common in patients with AHF, with many exhibiting moderate or severe levels of anemia. Greater severity of anemia correlates with older age, more comorbidities, and higher hospital admission rates, along with a trend toward higher mortality.

Clinical trial number

Not applicable.