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<p>MXenes (Ti<sub>3</sub>C<sub>2</sub>T<sub>X</sub>) and their composites exhibit exceptional electrical conductivity, flexibility, and biocompatibility, making them ideal for creating smart microrobots for targeted drug delivery, especially in cancer treatment. Their customizable surfaces enable precise navigation and targeted therapeutic release, improving efficacy and reducing side effects. They can also co-deliver multiple drugs for synergistic therapies. However, challenges in scalable production, stability, and regulation remain. Simultaneously, combining MXenes with quantum dots in polymer nanocomposites is revolutionizing multifunctional materials by merging electrical, optical, and catalytic properties. These composites enhance applications in drug delivery, tissue engineering, flexible electronics, and energy storage. Stimuli-responsive polymers allow controlled activation of embedded agents, though issues with scalability and clinical translation persist. This review underscores the potential of MXene- and quantum dot-based nanocomposites to drive innovation in biomedicine and sustainable technologies.</p>

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MXene quantum dot polymer nanocomposites as smart platforms for targeted drug delivery and multifunctional biomedical applications: an updated review

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年6月3日

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  • Mohammad Hossein Karami,
  • Omid Moini Jazani

摘要

MXenes (Ti3C2TX) and their composites exhibit exceptional electrical conductivity, flexibility, and biocompatibility, making them ideal for creating smart microrobots for targeted drug delivery, especially in cancer treatment. Their customizable surfaces enable precise navigation and targeted therapeutic release, improving efficacy and reducing side effects. They can also co-deliver multiple drugs for synergistic therapies. However, challenges in scalable production, stability, and regulation remain. Simultaneously, combining MXenes with quantum dots in polymer nanocomposites is revolutionizing multifunctional materials by merging electrical, optical, and catalytic properties. These composites enhance applications in drug delivery, tissue engineering, flexible electronics, and energy storage. Stimuli-responsive polymers allow controlled activation of embedded agents, though issues with scalability and clinical translation persist. This review underscores the potential of MXene- and quantum dot-based nanocomposites to drive innovation in biomedicine and sustainable technologies.