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Green synthesis of silver nanoparticle using pollen extract from Tetragonisca angustula a stingless bee

  • Ana Carolina Costa Santos,
  • Gabriela Carvalho Batista,
  • Rafaela Cavalcante Cerqueira,
  • Mariana Gonçalves Lisboa,
  • Joberth Lee Correa,
  • Tamiris Sabrina Rodrigues,
  • Murillo Néia Thomaz da Silva,
  • Vinícius Prado Bittar,
  • Serena Mares Malta,
  • Natalia Carine Lima dos Santos,
  • Foued Salmen Espindola,
  • Ana Maria Bonetti,
  • Carlos Ueira-Vieira

摘要

This study explores the green synthesis of silver nanoparticles (AgNPs) using a methanolic extract of fermented pollen from Tetragonisca angustula, a species of stingless bees. The AgNPs exhibit spherical morphology, low charge values, and suspension stability, with their unique composition attributed to elements from the pollen extract. Antioxidant assays show comparable activity between the pollen extract and AgNPs, emphasizing the retention of antioxidant effects. The synthesized AgNPs demonstrate antimicrobial activity against multidrug-resistant bacteria, highlighting their potential in combating bacterial resistance. The AgNPs exhibit no toxic effects on Drosophila melanogaster and even enhance the hatching rate of eggs. The study underscores the innovative use of stingless bee pollen extract in green synthesis, offering insights into the varied applications of AgNPs in biomedicine.