<p>A novel antibacterial agent was synthesized from Japanese cedar sawdust, a representative woody biomass resource, through chemical modification using potassium permanganate. The oxidation treatment introduced carboxyl groups onto the biomass surface, providing active sites for Ag<sup>+</sup> adsorption. X-ray photoelectron spectroscopy (XPS) analysis revealed characteristic Ag 3d peaks at 367.8 and 373.8&#xa0;eV, confirming the successful adsorption of Ag<sup>+</sup> onto the modified biomass. The saturated adsorption capacities of Ag<sup>+</sup> were determined to be 48.3&#xa0;mg&#xa0;g<sup>−&#xa0;1</sup> by the batch method and 73.5&#xa0;mg&#xa0;g<sup>−&#xa0;1</sup> by the column method. The antibacterial activity of the resulting Ag<sup>+</sup>-adsorbed material (Cedar-O-Ag) was evaluated against <i>Escherichia coli</i> by observing turbidity, Ag<sup>+</sup> release, and colony formation. Cedar-O-Ag induced bacterial cell lysis, with complete bactericidal activity observed at 50&#xa0;mg, corresponding to an Ag<sup>+</sup> concentration of 0.347&#xa0;mmol L<sup>−&#xa0;1</sup>. Colony formation assays confirmed that <i>E. coli</i> growth was entirely inhibited at this concentration. Furthermore, reusability tests demonstrated that Cedar-O-Ag maintained bactericidal activity for up to three consecutive cycles. Overall, these results show that woody biomass can serve as an effective, sustainable, and reusable carrier for antibacterial materials.</p>

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Preparation and evaluation of antibacterial activity of Ag+ supported modified Japanese cedar biomass

  • Masaki Tsujimoto,
  • Ryoya Murata,
  • Rai Matsushita,
  • Shigeru Miyata,
  • Toshiyuki Miyauchi

摘要

A novel antibacterial agent was synthesized from Japanese cedar sawdust, a representative woody biomass resource, through chemical modification using potassium permanganate. The oxidation treatment introduced carboxyl groups onto the biomass surface, providing active sites for Ag+ adsorption. X-ray photoelectron spectroscopy (XPS) analysis revealed characteristic Ag 3d peaks at 367.8 and 373.8 eV, confirming the successful adsorption of Ag+ onto the modified biomass. The saturated adsorption capacities of Ag+ were determined to be 48.3 mg g− 1 by the batch method and 73.5 mg g− 1 by the column method. The antibacterial activity of the resulting Ag+-adsorbed material (Cedar-O-Ag) was evaluated against Escherichia coli by observing turbidity, Ag+ release, and colony formation. Cedar-O-Ag induced bacterial cell lysis, with complete bactericidal activity observed at 50 mg, corresponding to an Ag+ concentration of 0.347 mmol L− 1. Colony formation assays confirmed that E. coli growth was entirely inhibited at this concentration. Furthermore, reusability tests demonstrated that Cedar-O-Ag maintained bactericidal activity for up to three consecutive cycles. Overall, these results show that woody biomass can serve as an effective, sustainable, and reusable carrier for antibacterial materials.