Abstract <p>Osteoarthritis is one of the most common diseases in veterinary medicine. In horses, this disease is often considered the main cause of termination of the athletic career. The therapy of this disease is mainly focused on the management of the underlying clinical symptoms. Traditional treatments include the use of medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), analgesics, corticosteroids, and chondroprotectors. Surgical methods are also often used. Some of the most effective therapies are now methods of regenerative medicine. Cell therapy, vesicle-based therapy, and gene therapy are mainly used. The aim of this review is to show information about regenerative medicine methods and to describe cases of their application in veterinary practice and in scientific research projects.</p>

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Application of Cellular and Genetic Technologies in the Therapy of Osteoarthritis in Horses: Analysis of Clinical Cases

  • A. M. Aimaletdinov,
  • A. G. Malanyeva,
  • E. Y. Zakirova

摘要

Abstract

Osteoarthritis is one of the most common diseases in veterinary medicine. In horses, this disease is often considered the main cause of termination of the athletic career. The therapy of this disease is mainly focused on the management of the underlying clinical symptoms. Traditional treatments include the use of medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), analgesics, corticosteroids, and chondroprotectors. Surgical methods are also often used. Some of the most effective therapies are now methods of regenerative medicine. Cell therapy, vesicle-based therapy, and gene therapy are mainly used. The aim of this review is to show information about regenerative medicine methods and to describe cases of their application in veterinary practice and in scientific research projects.