Abstract <p>Composite calcium phosphate coatings on VT 6 titanium substrates were obtained by electrochemical deposition from a CaCO<sub>3</sub>/Ca(H<sub>2</sub>PO<sub>4</sub>)<sub>2</sub> suspension electrolyte at a current density of 30 mA/cm<sup>2</sup> and a deposition time of 5 min. Biomimetic apatite was formed on the composite coatings by soaking them in a concentrated (3 times) model solution of Simulated Body Fluid (SBF × 3) and crystallization during heat treatment at 800°C for 5 h. The two-layer calcium phosphate coatings consisted of hydroxyapatite (71%), calcium oxide (23%) and β-tricalcium phosphate (6%). Three-layer porous bioactive coatings enriched with apatite were obtained by soaking of two-layer coatings in a 3 × SBF solution. In vivo, changes in the phase composition of different coating types were observed during implantation on the parietal bone of rats for 1, 3, and 6 months, indicating resorption processes and interaction with host tissue. Titanium implants with multilayer calcium phosphate coatings are not rejected by the body, provide accelerated fusion with bone tissue, and can be used in neurosurgery, dentistry, and orthopedics.</p>

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Physicochemical Properties of Titanium Implants with Multilayer Calcium Phosphate Coatings

  • A. E. Doroshenko,
  • V. K. Krut’ko,
  • O. N. Musskaya,
  • A. I. Dovnar,
  • O. B. Ostrovskaya,
  • A. I. Kulak

摘要

Abstract

Composite calcium phosphate coatings on VT 6 titanium substrates were obtained by electrochemical deposition from a CaCO3/Ca(H2PO4)2 suspension electrolyte at a current density of 30 mA/cm2 and a deposition time of 5 min. Biomimetic apatite was formed on the composite coatings by soaking them in a concentrated (3 times) model solution of Simulated Body Fluid (SBF × 3) and crystallization during heat treatment at 800°C for 5 h. The two-layer calcium phosphate coatings consisted of hydroxyapatite (71%), calcium oxide (23%) and β-tricalcium phosphate (6%). Three-layer porous bioactive coatings enriched with apatite were obtained by soaking of two-layer coatings in a 3 × SBF solution. In vivo, changes in the phase composition of different coating types were observed during implantation on the parietal bone of rats for 1, 3, and 6 months, indicating resorption processes and interaction with host tissue. Titanium implants with multilayer calcium phosphate coatings are not rejected by the body, provide accelerated fusion with bone tissue, and can be used in neurosurgery, dentistry, and orthopedics.