Abstract <p>Millions of people worldwide suffer from aortic valve disease. The aortic valve neocuspidization (AVNeo) procedure is one of the most efficient treatments for a dysfunctional aortic valve. The effectiveness of AVNeo depends directly on the suitability of the neovalve for the patient geometry of the aortic root. Choosing the optimal leaflet size and shape is the main problem when using AVNeo. The coaptation characteristics determine the degree of optimality of the neovalve. We present a personalized technology for patient-specific assessment of coaptation of the reconstructed aortic valve based on the low order shell formulation for the neovalve mechanics. We propose an ad-hoc algorithm for embedding neocusps into the aortic lumen and demonstrate its robustness on 6 human and 21 porcine geometries of the aortic roots. The numerical experiments show the practical intractability of the static equilibrium formulation and we propose the dynamic formulation. For the first time, to our knowledge, we introduce uniquely computed versions of definitions for the coaptation zone and related coaptation characteristics.</p>

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Numerical Issues of Patient-Specific Assessment of Reconstructed Aortic Valve

  • A. Liogky

摘要

Abstract

Millions of people worldwide suffer from aortic valve disease. The aortic valve neocuspidization (AVNeo) procedure is one of the most efficient treatments for a dysfunctional aortic valve. The effectiveness of AVNeo depends directly on the suitability of the neovalve for the patient geometry of the aortic root. Choosing the optimal leaflet size and shape is the main problem when using AVNeo. The coaptation characteristics determine the degree of optimality of the neovalve. We present a personalized technology for patient-specific assessment of coaptation of the reconstructed aortic valve based on the low order shell formulation for the neovalve mechanics. We propose an ad-hoc algorithm for embedding neocusps into the aortic lumen and demonstrate its robustness on 6 human and 21 porcine geometries of the aortic roots. The numerical experiments show the practical intractability of the static equilibrium formulation and we propose the dynamic formulation. For the first time, to our knowledge, we introduce uniquely computed versions of definitions for the coaptation zone and related coaptation characteristics.