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Abstract <p>Based on the architecture and coevolution of allosteric materials, a mechanical model of the erythrocyte is proposed. This model is used to explain such phenomena as erythrocyte flickering and phase transitions (morphological changes) at 49.5°C, which are not fully explained from the physical point of view. To describe the viscoelastic properties of proteins (in particular, for hemoglobin), experimental data obtained earlier are taken. The difference in viscoelastic properties between different forms of hemoglobin obtained earlier is used to describe the forces that are necessary to turn on and off the springs in the spectrin network.</p>

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Mechanical Model of Erythrocyte: Allostery at the Cellular Level?

  • 期刊论文

  • 发表日期：

    2025年8月1日

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  • S. G. Gevorkian,
  • D. S. Gevorgyan,
  • Y. A. Dyakov

摘要

Abstract

Based on the architecture and coevolution of allosteric materials, a mechanical model of the erythrocyte is proposed. This model is used to explain such phenomena as erythrocyte flickering and phase transitions (morphological changes) at 49.5°C, which are not fully explained from the physical point of view. To describe the viscoelastic properties of proteins (in particular, for hemoglobin), experimental data obtained earlier are taken. The difference in viscoelastic properties between different forms of hemoglobin obtained earlier is used to describe the forces that are necessary to turn on and off the springs in the spectrin network.