Synthesis, Spectral, and Structural Investigations and Anticancer Activity In Vitro of the New Organotin Complexes

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发表日期：

2024年3月1日

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P. A. Storozhenko,
I. S. Veselova,
E. V. Ovechkina,
A. A. Grachev,
A. A. Korlyukov,
A. D. Volodin,
E. Yu. Rybalkina,
A. K. Shestakova,
V. I. Shiryaev

摘要

Abstract

The series of new organotin complexes on the basis of bis(trimethylsilylmethyl)tin diсhloride, 1,1-dichloro-1-stanna-3,3,5,5-tetramethyl-3,5-disila-4-oxacyclohexane, and mono- and bidentate ligands—2,2'-bipyridyl, 1,10-phenanthroline, and 1-methyl-, 1-vinyl-, and 1-allylimidazoles—have been synthesized. The complexes were characterized by elemental analysis; ¹Н-, ¹³С-, and ¹¹⁹Sn-NMR spectrometry; and X-ray data. Cytotoxicity in vitro of the complexes for some lines of human cancer cells was investigated.