Scholarlink

<p>The review summarizes the main peculiarities of rodent audiogenic epilepsy (seizures in response to loud sound), which is related to brain neurochemistry and morphology as well as to the disturbances of muscle tone regulation. The Krushinsky–Molodkina rat strain selectively bred for audiogenic epilepsy is the valuable genetic model of human seizure states. The pattern of neurochemical disturbances in this strain is similar to those in other rodent strains with audiogenic epilepsy, which permit to suggest the non-random nature of these phenomena. The postictal catalepsy and cataleptic states of other types are discussed in relation with audiogenic seizure fits. Brain anomalies in these animals emerge, presumably, during early ontogeny.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Audiogenic Seizures and Postictal Catalepsy in Rats of Krushinsky–Molodkina Strain

  • 期刊论文

  • 发表日期：

    2025年9月1日

查看全文
  • N. M. Surina,
  • I. B. Fedotova,
  • I. I. Poletaeva

摘要

The review summarizes the main peculiarities of rodent audiogenic epilepsy (seizures in response to loud sound), which is related to brain neurochemistry and morphology as well as to the disturbances of muscle tone regulation. The Krushinsky–Molodkina rat strain selectively bred for audiogenic epilepsy is the valuable genetic model of human seizure states. The pattern of neurochemical disturbances in this strain is similar to those in other rodent strains with audiogenic epilepsy, which permit to suggest the non-random nature of these phenomena. The postictal catalepsy and cataleptic states of other types are discussed in relation with audiogenic seizure fits. Brain anomalies in these animals emerge, presumably, during early ontogeny.