Copolymers of Acrylamides and Acrylic Acid with Antiviral Activity

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发表日期：

2024年8月1日

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E. F. Panarin,
O. N. Zhuravskaya,
A. V. Sitko,
E. N. Vlasova,
A. A. Shtro

摘要

Abstract—

Carboxylic polyelectrolytes, water-soluble copolymers of acrylic acid and N-substituted acrylamides, were synthesized for the first time by reactions in the chains of poly(acrylic anhydride) with aromatic amines. The structure, composition, and molecular weight characteristics of the copolymers were determined. The possibility of synthesizing alternating copolymers of acrylic acid was demonstrated. The copolymers of varying composition characterized by low cytotoxicity and activity against herpes simplex virus were prepared.