Abstract <p>In heavy ion accelerators, special attention is paid to the processes of electron loss and capture by ions during interaction with the residual gas. A change in the ion charge leads to their loss on the vacuum chamber walls. As a result of ion-stimulated desorption processes, the concentration of residual gas locally increases, which, in turn, can lead to an avalanche-like increase in beam intensity loss, or so-called vacuum instability. A booster synchrotron with electron cooling for technological applications is being developed at the Budker Institute of Nuclear Physics, Siberian Branch, Russian Academy of Sciences (BINP SB RAS). The processes of vacuum instability and various mechanisms of its suppression are simulated as part of its design.</p>