Abstract <p><i>trans</i>-Stilbene reacted with alkyl thiocyanates in concentrated sulfuric acid to give 1-alkylsulfanyl-3-phenyl-3,4-dihydroisoquinolines which were converted into 3-phenyl-3,4-dihydroisoquinolin-1(2<i>H</i>)-one upon silica gel chromatography.</p>

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A Simple Synthesis of 3-Phenyl-3,4-dihydroisoquinolin-1(2H)-one

  • A. A. Smolyak,
  • A. S. Pegushina,
  • A. A. Gorbunov,
  • Yu. V. Shklyaev

摘要

Abstract

trans-Stilbene reacted with alkyl thiocyanates in concentrated sulfuric acid to give 1-alkylsulfanyl-3-phenyl-3,4-dihydroisoquinolines which were converted into 3-phenyl-3,4-dihydroisoquinolin-1(2H)-one upon silica gel chromatography.