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Abstract <p>2-(2-Haloaryloxy)acetonitriles reacted with nitromethane in the presence of DBU and copper(I) iodide to afford 4-nitro-2<i>H</i>-chromen-3-amines as a result of consecutive arylation and aza-Henry reactions.</p>

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Copper-Catalyzed C–C-Coupling/Aza-Henry Domino Reaction of Nitriles to Synthesize 4-Nitro-2H-chromen-3-amines

  • 期刊论文

  • 发表日期：

    2025年7月1日

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  • E. A. Sokolova,
  • A. S. Petryakova,
  • D. A. Sarmutdinova,
  • O. A. Sherstneva,
  • A. A. Festa,
  • L. G. Voskressensky

摘要

Abstract

2-(2-Haloaryloxy)acetonitriles reacted with nitromethane in the presence of DBU and copper(I) iodide to afford 4-nitro-2H-chromen-3-amines as a result of consecutive arylation and aza-Henry reactions.