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Abstract <p>We developed the electrochemical synthesis of isoxazolines from aldoximes and EWG-substituted alkenes with the assistance of the in situ generated hypervalent iodine compounds. A wide range of substituted isoxazolines possessing fungicidal activity were obtained in 20–48% yields under constant current conditions in an undivided cell.</p>

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Electrochemical Synthesis of Isoxazolines from Aldoximes and EWG-Substituted Alkenes Enabling by In Situ Generated Hypervalent Iodine Compounds

  • 期刊论文

  • 发表日期：

    2025年6月1日

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  • O. V. Bityukov,
  • A. S. Kirillov,
  • V. A. Vil’,
  • G. I. Nikishin,
  • A. O. Terent’ev

摘要

Abstract

We developed the electrochemical synthesis of isoxazolines from aldoximes and EWG-substituted alkenes with the assistance of the in situ generated hypervalent iodine compounds. A wide range of substituted isoxazolines possessing fungicidal activity were obtained in 20–48% yields under constant current conditions in an undivided cell.