Synthesis of 4-(4-Azidobenzyl)phenol and N-[4-(4-Azidobenzyl)phenyl]acetamide
摘要
Abstract
N-[4-(4-Azidobenzyl)phenyl]acetamide and 4-(4-azidobenzyl)phenol have been synthesized in 57 and 55% yields, respectively, by the diazotization of N-[4-(4-aminobenzyl)phenyl]acetamide and 4-(4-aminobenzyl)phenol with sodium nitrite in excess hydrochloric acid, followed by treatment of the resulting diazonium salts with sodium azide at 0 to –5°C.