Scholarlink

Abstract <p>The chromenopyrimidine scaffold is an important building block for many medicinally active new chemicals. In the current work, a series of 2<i>H</i>-chromene 1,3-dimethylpyrimidine-2,4-dione derivatives have been synthesized by a one-pot three-component reaction between 4-hydroxy-2<i>H</i>-chromen-2-one, substituted benzaldehydes, and 6-amino-1,3-dimethylpyrimidine-2,4(1<i>H</i>,3<i>H</i>)-dione <b>3</b> at 65–70°C for 30–40 min using [BMIM]BF<sub>4</sub> as green reaction medium.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

[BMIM]BF4-Mediated One-Pot Synthesis of 1,3-Dimethylpyrimidine-2,4-dione Derivatives Containing a 2H-Chromene Moiety

  • 期刊论文

  • 发表日期：

    2025年4月23日

查看全文
  • N. Ganapathi Chary,
  • Madhusudhan Gutta,
  • K. Vidya

摘要

Abstract

The chromenopyrimidine scaffold is an important building block for many medicinally active new chemicals. In the current work, a series of 2H-chromene 1,3-dimethylpyrimidine-2,4-dione derivatives have been synthesized by a one-pot three-component reaction between 4-hydroxy-2H-chromen-2-one, substituted benzaldehydes, and 6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione 3 at 65–70°C for 30–40 min using [BMIM]BF4 as green reaction medium.