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Abstract <p>Ribavirin analogues were synthesized starting from D-glucose through a series of reactions. The structure of the synthesized compounds was confirmed by IR, NMR, and mass spectrometry. Their nucleosidase enzyme inhibitory activity was tested using TLC bioautography. Almost all of the compounds exhibited enzyme inhibitory activity.</p>

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Bioautography and Synthesis of Ribavirin Analogues as Possible Nucleosidase Inhibitors

  • 期刊论文

  • 发表日期：

    2025年3月1日

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  • A. Srinivas

摘要

Abstract

Ribavirin analogues were synthesized starting from D-glucose through a series of reactions. The structure of the synthesized compounds was confirmed by IR, NMR, and mass spectrometry. Their nucleosidase enzyme inhibitory activity was tested using TLC bioautography. Almost all of the compounds exhibited enzyme inhibitory activity.