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Synthesis of the C1–C9 Block of Epothilone D Analogue

  • 期刊论文

  • 发表日期：

    2024年12月1日

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  • G. R. Sunagatullina,
  • M. S. Miftakhov

摘要

Abstract

(2R,5R,6S,7S,9E)-2-{[tert-Butyl(dimethyl)silyl]oxy}-3,3,5,7-tetramethyl-4-oxo-6-[(triethylsilyl)oxy]undec-9-enoic acid has been synthesized as the C1–C9 block necessary for the subsequent incorporation into the structure of a desired epothilone D analogue.