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Three-Component Synthesis of Tetrahydroisoquinolines via SNVin Reaction

  • 期刊论文

  • 发表日期：

    2024年9月1日

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  • I. V. Dyachenko,
  • V. D. Dyachenko,
  • P. V. Dorovatovskii,
  • V. N. Khrustalev,
  • V. G. Nenajdenko

摘要

Abstract

The three-component reaction of carbocyclic enamino ketones, CH acids, and electrophiles has been studied. Previously unknown 5,6,7,8-tetrahydroisoquinoline derivatives have been synthesized via nucleophilic vinylic substitution (SNVin). The structures of some of the obtained compounds have been determined by X-ray analysis.