Synthesis of Tetrazolo[1,5-a]pyrimidines Derivatives by Using Nanocatalyst of MOF Supported on the Red Soil

MOF supported on the red soil was synthesized thru simple method by Cu˗MOF and red soil with ratio of 1 : 5. The structure and morphology of MOF supported on the red soil was considered by FTIR and Raman spectroscopy, FESEM, TGA and BET methods. The results showed MOF supported on the red soil have mesoporous nanostructure (20–25 nm). A simple and efficient synthesis of tetrazolo[1,5-a]pyrimidines was accomplished by three-component reaction of a mixture of aromatic aldehyde, 5-aminotetrazole and ethyl acetoacetate or methyl acetoacetate using MOF supported on the red soil as heterogenic catalyst. The reactions were carried out in water and ethanol at 70°C. MOF supported on the red soil operated as a sufficient recyclable, effective, low cost and eco-friendly catalyst for synthesis of tetrazolo [1,5-a] pyrimidines.