Reactions of Oxazol-5(4H)-ones Involving Organosilicone Reagents (A Review)

The review summarizes, systematizes, and analyzes the published data concerning the reactions of saturated and unsaturated oxazol-5(4H)-ones with various organosilicon reagents. Examples of the synthesis of heterocyclic compounds, 4,4-disubstituted oxazol-5(4H)-ones, and α,α-disubstituted α-amino acids and their esters by these reactions are considered. For some processes, plausible mechanisms are presented. Examples of the synthesis of biologically active and natural compounds based on reactions involving oxazol-5(4H)-ones and organosilicon reagents are described.