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Synthesis of Ethyl 4-Aryl-2-imino-1-(2-methoxyphenyl)-5-[(2-methoxyphenyl)carbamoyl]-6-oxopiperidine-3-carboxylates

  • A. Kh. Khachatryan,
  • K. A. Avagyan,
  • A. A. Sargsyan,
  • A. E. Badasyan

摘要

Abstract

The reaction of ethyl 3-aryl-2-cyanoprop-2-enoates with N1,N3-bis(2-methoxyphenyl)propanedi­amide afforded previously unknown products of intramolecular heterocyclization of the primary Michael adducts, ethyl 4-aryl-2-imino-1-(2-methoxyphenyl)-5-[(2-methoxyphenyl)carbamoyl]-6-oxopiperidine-3-car­box­ylates, in 73–90% yields. The product structure was determined by IR and NMR (1H, 13C) spectroscopy.