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Cyclocondensation of Methyl 5-Methyl-1-(2-oxo-2-phenylethyl)-1H-pyrazole-3-carboxylate. Synthesis of a New 18-Membered Nitrogen Macroheterocycle

  • A. O. Kharaneko,
  • T. M. Pekhtereva,
  • O. I. Kharaneko,
  • A. S. Morkovnik

摘要

Abstract

A method has been developed for the synthesis of a new 18-membered nitrogen macroheterocycle via acid-catalyzed cyclocondensation of 1-[(2E,Z)-2-hydrazinylidene-2-phenylethyl]-5-methyl-1H-pyrazole-3-carbohydrazide which was obtained by hydrazinolysis of methyl 5-methyl-1-(2-oxo-2-phenylethyl)-1H-pyra­zole-3-carboxylate.