Cyclocondensation of Methyl 5-Methyl-1-(2-oxo-2-phenylethyl)-1H-pyrazole-3-carboxylate. Synthesis of a New 18-Membered Nitrogen Macroheterocycle
摘要
Abstract
A method has been developed for the synthesis of a new 18-membered nitrogen macroheterocycle via acid-catalyzed cyclocondensation of 1-[(2E,Z)-2-hydrazinylidene-2-phenylethyl]-5-methyl-1H-pyrazole-3-carbohydrazide which was obtained by hydrazinolysis of methyl 5-methyl-1-(2-oxo-2-phenylethyl)-1H-pyrazole-3-carboxylate.