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Synthesis of (S)-N-Ethyl-2-(5-methylidene-4-oxocyclopent-2-en-1-yl)acetamide―A Model exo-Methylidenecyclopentenone Bioisoster of Prostamides

  • A. M. Gimazetdinov,
  • Z. R. Makaev,
  • M. S. Miftakhov

摘要

Abstract

exo-Methylidenecyclopentenonee amide is synthesized from methyl 2-[({(1R,2R,5R)-2-{[(tert-butyl(dimethyl)silyl]oxymethyl})-5-(trimethylsilyl)cyclopent-3-en-1-yl]acetate.